CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Targeted identification of iron regulated genes in patients with hemochromatosis and hepatitis C using a whole genome cDNA microarray
DOI 10.1055/s-2008-1037620
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Nachweis in CareLit
Autor:innenS Hagist, U Hebling, D Kiesslich, A Poustka, H Sültmann, HK Seitz, S Mueller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Chronic iron accumulation is an important risk factor for disease progression in chronic hepatitis C (HCV), however, the underlying mechanisms are poorly understood. We here introduce a novel approach to search for iron-regulated genes in liver disease by a) whole genome screening in iron-depleted and – overloaded cultured cells and b) validating selected genes as markers of altered iron metabolism in patients…
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Zitierempfehlung
S Hagist, U Hebling, D Kiesslich, A Poustka, H Sültmann, HK Seitz, S Mueller (2008) Targeted identification of iron regulated genes in patients with hemochromatosis and hepatitis C using a whole genome cDNA microarray. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037620
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