CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatitis B Virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans
DOI 10.1055/s-2008-1037636
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Autor:innenA Schulze, S Seitz, P Gripon, S Urban
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Contrary to many other viruses, the initial steps of the Hepatitis B virus (HBV) infection, including attachment, specific receptor interaction and membrane fusion, are unsolved. Using the susceptible HepaRG cells as an in vitro cell culture system, we here report that HBV entry into hepatocytes requires the large envelope protein (L)-dependent interaction with cell-surface glycosaminoglycans (GAG). HBV infection wa…
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Zitierempfehlung
A Schulze, S Seitz, P Gripon, S Urban (2008) Hepatitis B Virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037636
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