CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Protection by HLA-B27 in HCV infection: role of virological and immunological factors
DOI 10.1055/s-2008-1037648
Bibliografische Angaben
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Autor:innenC Neumann-Haefelin, E Dazert, HE Blum, R Bartenschlager, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
B27 is a highly protective HLA allele in HCV infection. Indeed, 80% of B27+ Irish women with accidental HCV genotype 1b infection resolved the infection spontaneously while only 20% developed chronic infection (McKiernan et al., Hepatology 2004). We recently linked this protective effect of HLA-B27 as well as viral evolution within the few B27+ individuals who developed chronic infection to a single, immunodominant…
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Zitierempfehlung
C Neumann-Haefelin, E Dazert, HE Blum, R Bartenschlager, R Thimme (2008) Protection by HLA-B27 in HCV infection: role of virological and immunological factors. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037648
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