CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The CYP450 mouse model for autoimmune liver disease: Breaking of self-tolerance in transgenic CYP2D6-mice by viral infection
DOI 10.1055/s-2008-1037649
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Autor:innenM Holdener, E Hintermann, EF Johnson, MP Manns, MG von Herrath, U Christen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC), often have severe consequences for the patient. Because of a lack of appropriate animal models not much is known about their potential viral etiology. Infection by liver-tropic viruses is one possibility for the breakdown of self-tolerance. We therefore infected mice with an Adenovirus expressing the natural human auto…
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Zitierempfehlung
M Holdener, E Hintermann, EF Johnson, MP Manns, MG von Herrath, U Christen (2008) The CYP450 mouse model for autoimmune liver disease: Breaking of self-tolerance in transgenic CYP2D6-mice by viral infection. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037649
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