CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatic cytochrome P450 2E1, steatosis and fibrosis in alcoholic and non-alcoholic steatohepatitis
DOI 10.1055/s-2008-1037674
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Glassen, S Mueller, R Waldherr, P Becker, F Stickel, S Friedrich, HK Seitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Since alcoholic steatohepatitis (ASH) and non-alcoholic steatohepatitis (NASH) cannot be distinguished by histopathology, similar pathogenetic mechanisms may be involved in the development of steatohepatitis from fatty liver. One of these mechanisms is oxidative stress. Ethanol as well as free fatty acids induce cytochrome P4502E1 (CYP2E1) which generates reactive oxygen species (ROS) leading to lipid peroxidation,…
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Zitierempfehlung
K Glassen, S Mueller, R Waldherr, P Becker, F Stickel, S Friedrich, HK Seitz (2008) Hepatic cytochrome P450 2E1, steatosis and fibrosis in alcoholic and non-alcoholic steatohepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037674
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