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Uptake and Distribution of the Estramustine-Phosphate Metabolite Estramustine after Single-Dose Injection in Patients with Prostatic Cancer

P. H. Walz, P. Björk, K. Edman, P. O. Gunnarsson, B. Hartley-Asp · Aktuelle Urologie · Ausgabe S 1/1996 · S. 92-93

DOI 10.1055/s-2008-1055666

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Autor:innenP. H. Walz, P. Björk, K. Edman, P. O. Gunnarsson, B. Hartley-Asp
ZeitschriftAktuelle Urologie
AusgabeS 1/1996
Jahrgang / SeitenJg. 27 · S. 92-93

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Summary: The concentration of estramustine (EaM) in serum and tumor tissue of 19 patients with prostatic carcinoma was determined after single i. v. injection of estramustine phosphate (300 or 600 mg) administered 12 to 15.5 hours prior to radical prostatectomy. The concentration (mean ± SD) was 21.9 ± 10.3 ng/ml in serum and 234 ± 168 ng/g in the tumor tissue. In patients treated with 300 mg the tumor tissue: serum…

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P. H. Walz, P. Björk, K. Edman, P. O. Gunnarsson, B. Hartley-Asp (1996) Uptake and Distribution of the Estramustine-Phosphate Metabolite Estramustine after Single-Dose Injection in Patients with Prostatic Cancer. Aktuelle Urologie, 27 (S 1), 92-93. https://doi.org/10.1055/s-2008-1055666

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