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Individual assessment of chronic brain tissue changes in MRI – the role of focal lesions for brain atrophy development. A Voxel-Guided Morphometry study

M Kraemer, T Schormann, A Dabringhaus, J Hirsch, KM Stephan, V Hömberg, L Kappos, A Gass · Klinische Neurophysiologie · Ausgabe 04/2008

DOI 10.1055/s-2008-1072980

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Autor:innenM Kraemer, T Schormann, A Dabringhaus, J Hirsch, KM Stephan, V Hömberg, L Kappos, A Gass
ZeitschriftKlinische Neurophysiologie
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Despite considerable progress in the treatment of MS, it is still the most frequent cause of neurological disability in young and middle-aged adults. The known neuropathological mechanisms leading to progressive disability are immune-mediated demyelination and axonal loss. Several MRI studies demonstrated brain volume reduction, consisting of white and grey matter loss as an in vivo marker of MS. As this brain atrop…

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M Kraemer, T Schormann, A Dabringhaus, J Hirsch, KM Stephan, V Hömberg, L Kappos, A Gass (2008) Individual assessment of chronic brain tissue changes in MRI – the role of focal lesions for brain atrophy development. A Voxel-Guided Morphometry study. Klinische Neurophysiologie (04). https://doi.org/10.1055/s-2008-1072980

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