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Increase of spontaneous lung metastasis of small cell lung cancer in the absence of Natural Killer cells in Pfp/Rag2 double knock out mice

S Sodeur, S Ullrich, H Gustke, U Zangemeister-Wittke, U Schumacher · Pneumologie · Ausgabe 04/2008

DOI 10.1055/s-2008-1074188

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Autor:innenS Sodeur, S Ullrich, H Gustke, U Zangemeister-Wittke, U Schumacher
ZeitschriftPneumologie
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Most patients with small-cell lung cancer (SCLC) suffer from extensive disease and early metastatic spread, with an unimproved poor prognosis. The mechanisms of metastatic spread are still poorly understood. Earlier animal models of SCLC were of limited clinical value, as the process of metastasis was inefficient and had to be initialized by i.v. injection of human SCLC cells (dissemination) or orthoto…

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Zitierempfehlung

S Sodeur, S Ullrich, H Gustke, U Zangemeister-Wittke, U Schumacher (2008) Increase of spontaneous lung metastasis of small cell lung cancer in the absence of Natural Killer cells in Pfp/Rag2 double knock out mice. Pneumologie (04). https://doi.org/10.1055/s-2008-1074188

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