CareLit · DOI-Nachweis · Pneumologie
Role of Hypoxia Inducible Factor (HIF) and NADPH oxidases in regulation of Kv channels in pulmonary artery smooth muscle cells
DOI 10.1055/s-2008-1074194
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Mittal, M Roth, R Schermuly, HA Ghofrani, W Seeger, F Grimminger, N Weißmann
ZeitschriftPneumologie
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Hypoxia sensitive voltage gated K++ channels have been widely hypothesised for their role in regulating the contractility and growth of pulmonary artery smooth muscle cells (PASMC). Acute hypoxia leads to the inhibition of the hypoxia sensitive Kv channels whereas chronic hypoxia down-regulates their expression at both, mRNA and protein level in isolated rat PASMCs. Regarding the regulation of various Kv…
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Zitierempfehlung
M Mittal, M Roth, R Schermuly, HA Ghofrani, W Seeger, F Grimminger, N Weißmann (2008) Role of Hypoxia Inducible Factor (HIF) and NADPH oxidases in regulation of Kv channels in pulmonary artery smooth muscle cells. Pneumologie (04). https://doi.org/10.1055/s-2008-1074194
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