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Expression, overrepresentation and mutations of EGFR in early-stage lung cancer

S Bode, S Scheil-Bertram, A Kruger, A Fisseler-Eckhoff · Pneumologie · Ausgabe 04/2008

DOI 10.1055/s-2008-1074242

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Autor:innenS Bode, S Scheil-Bertram, A Kruger, A Fisseler-Eckhoff
ZeitschriftPneumologie
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Since the introduction of tyrosine kinase inhibitors in therapy of Non Small Cell Lung Cancer (NSCLC) most studies on Epidermal Growth Factor Receptor (EGFR) aim at EGFR as prognostic and predictive factor in advanced NSCLC. While EGFR mutations are established as predictive and prognostic markers, the predictive and prognostic value of EGFR DNA-overrepresentation is discussed controversely. Moreover EGFR status mea…

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Zitierempfehlung

S Bode, S Scheil-Bertram, A Kruger, A Fisseler-Eckhoff (2008) Expression, overrepresentation and mutations of EGFR in early-stage lung cancer. Pneumologie (04). https://doi.org/10.1055/s-2008-1074242

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