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Nanohale – Cytotoxic and proinflammatory evaluation of various PEI particles on lung target cells

A Beyerle, O Merkel, H Schulz, T Kissel, T Stöger · Pneumologie · Ausgabe 04/2008

DOI 10.1055/s-2008-1074269

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Autor:innenA Beyerle, O Merkel, H Schulz, T Kissel, T Stöger
ZeitschriftPneumologie
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Various polyethylenimines (PEI) of different molecular weights and surface modifications have been described for DNA and siRNA gene delivery. However, their safety profile remains of major importance. For this reason a broad range of different modified PEI particles have been developed to reduce cytotoxicity. Promising approaches are: (i) PEI particles with low molecular weight, and (ii) surface modifications of the…

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Zitierempfehlung

A Beyerle, O Merkel, H Schulz, T Kissel, T Stöger (2008) Nanohale – Cytotoxic and proinflammatory evaluation of various PEI particles on lung target cells. Pneumologie (04). https://doi.org/10.1055/s-2008-1074269

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