CareLit · DOI-Nachweis · Pneumologie
Extracellular ATP triggers and maintains airway inflammation in human and murine models of asthma by activating dendritic cells
DOI 10.1055/s-2008-1074287
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Idzko, D Ferrari, F Di Virgilio, S Sorichter, B Lambrecht, J Virchow Jr
ZeitschriftPneumologie
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Extracellular nucleotides have a key signaling role in cell-to-cell communication. In particular, extracellular ATP can act at plasma membrane P2 receptors (P2R) and thus serve as a danger signal to alert the immune system of tissue damage during the early phases of inflammation. Here we show that allergen challenge causes acute accumulation of ATP not only in the airways of asthmatic subjects but also in ovalbumin…
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Zitierempfehlung
M Idzko, D Ferrari, F Di Virgilio, S Sorichter, B Lambrecht, J Virchow Jr (2008) Extracellular ATP triggers and maintains airway inflammation in human and murine models of asthma by activating dendritic cells. Pneumologie (04). https://doi.org/10.1055/s-2008-1074287
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