CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
RAGE deficiency induces a proinflammatory phenotype in bones and osteoblasts through PPAR-a suppression
DOI 10.1055/s-2008-1076175
Bibliografische Angaben
Nachweis in CareLit
Autor:innenSK Biswas, F Duttenhoefer, H Li, D Matte, JC Igwe, PM Humpert, C Kasperk, PP Nawroth, A Bierhaus
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Diabetes mellitus is associated with bone loss, increased fracture rate and reduced bone healing. Accumulation of advanced glycation end products (AGE) and associated overexpression of the receptor for AGE (RAGE) have been implicated in the pathogenesis of bone disease in diabetes. Although the AGE-RAGE interaction is well known for the sustained induction of inflammatory process, the physiologic role of RAGE…
Zitieren
Zitierempfehlung
SK Biswas, F Duttenhoefer, H Li, D Matte, JC Igwe, PM Humpert, C Kasperk, PP Nawroth, A Bierhaus (2008) RAGE deficiency induces a proinflammatory phenotype in bones and osteoblasts through PPAR-a suppression. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-2008-1076175
Mit CareLit weiterarbeiten