CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Inhibition of Glyoxalase 1 impairs physiological wound healing
DOI 10.1055/s-2008-1076180
Bibliografische Angaben
Nachweis in CareLit
Autor:innenTH Fleming, S Stoyanov, TM Theilen, U Zeuge, PJ Thornalley, P Humpert, M Brownlee, PP Nawroth, A Bierhaus
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Increased formation of the reactive dicarbonyl compound, methylglyoxal (MG), in vivo has been shown to be associated with the onset of microvascular disease and impaired wound healing. MG and other endogenously formed dicarbonyl compounds can react with proteins to form Advanced Glycation Endproducts (AGEs). Glyoxalase I (GLO1) is part of the glyoxalase system, and is the major cellular defence in the detoxification…
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Zitierempfehlung
TH Fleming, S Stoyanov, TM Theilen, U Zeuge, PJ Thornalley, P Humpert, M Brownlee, PP Nawroth, A Bierhaus (2008) Inhibition of Glyoxalase 1 impairs physiological wound healing. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-2008-1076180
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