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Transcription factor FBI-1 acts as a dual regulator in adipogenesis by coordinated regulation of cyclin-A and E2F-4

R Bilkovski, F Oberhäuser, A Droste, M Gomolka, U Leeser, M Udelhoven, W Krone, M Laudes · Diabetologie und Stoffwechsel · Ausgabe 04/2008

DOI 10.1055/s-2008-1076217

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Autor:innenR Bilkovski, F Oberhäuser, A Droste, M Gomolka, U Leeser, M Udelhoven, W Krone, M Laudes
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: Generation of new adipocytes plays a major role in the development of obesity. We previously have shown that transcriptional repressor FBI-1 exerts a dual effect in the process of adipogenesis by inhibiting proliferation and promoting differentiation of preadipocytes. The aim of the present study was to identify FBI-1 regulated molecular effectors which could account for these effects. Methods: In order to inv…

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Zitierempfehlung

R Bilkovski, F Oberhäuser, A Droste, M Gomolka, U Leeser, M Udelhoven, W Krone, M Laudes (2008) Transcription factor FBI-1 acts as a dual regulator in adipogenesis by coordinated regulation of cyclin-A and E2F-4. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-2008-1076217

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