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Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model for the metabolic syndrome

T Dreja, Z Jovanovic, A Rasche, R Kluge, R Herwig, HG Joost, G Yeo, H Al-Hasani · Diabetologie und Stoffwechsel · Ausgabe 04/2008

DOI 10.1055/s-2008-1076218

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Autor:innenT Dreja, Z Jovanovic, A Rasche, R Kluge, R Herwig, HG Joost, G Yeo, H Al-Hasani
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: NZL mice develop a polygenic disease pattern of obesity, hyperglycaemia and hyperinsulinemia which resembles the human metabolic syndrome. The prevalence for type-2 like diabetes is greatly increased in animals receiving a high-fat diet (HFD). However animals fed with a carbohydrate-free high fat-diet (CHFD) were protected from developing diabetes. In the present study NZL mice were fed HFD or CHFD and body we…

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Zitierempfehlung

T Dreja, Z Jovanovic, A Rasche, R Kluge, R Herwig, HG Joost, G Yeo, H Al-Hasani (2008) Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model for the metabolic syndrome. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-2008-1076218

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