CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
KLF11 differentially regulates PDX1-induced activation of the human insulin promoter in rodent beta cells and human non beta cells
DOI 10.1055/s-2008-1076418
Bibliografische Angaben
Nachweis in CareLit
Autor:innenN Perakakis, G Päth, X Niu, S van Loosen, M Alt, T Stahl, J Seufert
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: KLF11 is a pancreas enriched member of the Sp1/KLF transcription factor family which plays an important role in mammalian gene regulation. Previously we demonstrated that human (h)KLF11) inhibits human insulin promoter (hInsP) activity in rodent beta cell lines via an unknown mechanism. Here we present results from ongoing experiments in which we test the hypothesis that KLF11 interferes with the major hInsP t…
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Zitierempfehlung
N Perakakis, G Päth, X Niu, S van Loosen, M Alt, T Stahl, J Seufert (2008) KLF11 differentially regulates PDX1-induced activation of the human insulin promoter in rodent beta cells and human non beta cells. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-2008-1076418
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