CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Synthetic lethality screens of vichem compounds in P53 mutant syngenic cell line models
DOI 10.1055/s-2008-1079634
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Autor:innenB Hegymegi-Barakonyi, G Kéri, L Őrfi, Z Varga, Z Greff, Z Horváth, B Jóri, R Schwab, I Peták
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Kinase inhibitors are promising new class anticancer agents in gastrointestinal malignancies. Aims/methods: a focused compound library of 100 molecules was screened on wild type and p53 deficient colorectal cancer cell lines HCT116wt and HCT116-/-p53 to select a small subset of compounds for detailed characterization. In parallel to the apoptosis assays, luminescence based growth inhibition assays were…
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Zitierempfehlung
B Hegymegi-Barakonyi, G Kéri, L Őrfi, Z Varga, Z Greff, Z Horváth, B Jóri, R Schwab, I Peták (2008) Synthetic lethality screens of vichem compounds in P53 mutant syngenic cell line models. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-2008-1079634
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