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Selectivity profiling and off-target identification of clinically relevant kinase inhibitors for gastrointestinal tumors

G Kéri, A Ulrich, Z Varga, Z Greff, L Örfi, R Schwab, I Peták · Zeitschrift für Gastroenterologie · Ausgabe 05/2008

DOI 10.1055/s-2008-1079646

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Autor:innenG Kéri, A Ulrich, Z Varga, Z Greff, L Örfi, R Schwab, I Peták
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Targeted inhibition of protein kinases by small molecule drugs has evolved into a viable approach for anticancer therapy. These inhibitors are widely used in signal transduction therapy, although the true selectivity of them has remained unclear. Recently several kinase inhibitors have been used for Gastrointestinal tumors. We have developed a chemical derivatization based affinity chromatography technology for sele…

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G Kéri, A Ulrich, Z Varga, Z Greff, L Örfi, R Schwab, I Peták (2008) Selectivity profiling and off-target identification of clinically relevant kinase inhibitors for gastrointestinal tumors. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-2008-1079646

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