Gesundheitsökonomie & Qualitätsmanagement , Thieme Verlag Heft S 2-2005, Jahrgang 10) ISSN 1432-2625 Seite(n) 64 bis 69 DOI: 10.1055/s-2005-858484 CareLit-Dokument-Nr: 318600 |
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Zusammenfassung EAGLE (Economic Assessment of Glycemic Control and Long-term Effects) ist ein Diabetes-Simulationsmodell, das anhand modernster mathematisch-statistischer Methoden entwickelt und validiert wurde. Das Modell besteht aus einem epidemiologischen Modul, welches den klinischen Verlauf des Diabetes anhand verschiedener Einflussfaktoren und Behandlungen simuliert, und einem gesundheitsökonomischen Modul, welches den klinisch-epidemiologischen Ergebnissen Kosten zuordnet und modernste ökonomische Analysen ermöglicht. Die mathematische Basis des Modells bilden Daten aus drei großen Diabetes-Studien: United Kingdom Prospective Diabetes Study (UKPDS), Diabetes Control and Complications Trial (DCCT) und Wisconsin Epidemiology Study of Diabetic Retinopathy (WESDR). Im Weiteren wird auf die ausführliche Bezeichnung des EAGLE-Modells Version 2.0_IV verzichtet und lediglich auf das EAGLE-Modell verwiesen. Abstract EAGLE (Economic Assessment of Glycemic Control and Long-term Effects) is a diabetes simulation model, which was developed and validated according to state-of-the-art statistic and mathematic methods. The model consists of an epidemiological module, which simulates the clinical development of diabetes according to various influence parameters and treatments, and a health economic module, which assigns costs to the epidemiological results and permits up to date economic analyses. The mathematic basis of the model is built on data of three big clinical trials: United Kingdom Prospective Diabetes Study (UKPDS), Diabetes Control and Complications Trial (DCCT) und Wisconsin Epidemiology Study of Diabetic Retinopathy (WESDR). Schlüsselwörter Krankheitsmodelle - Kosteneffektivität - Diabetes mellitus - Gesundheitsökonomie Key words Modelling - simulation - diabetes mellitus - cost effectiveness - health economics Literatur 1 Clarke P M, Gray A M, Briggs A. et al . 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Analysis of the health benefits and cost-effectiveness of treating NIDDM with the goal of normoglycemia. Diabetes Care. 1997; 20 735-744 PubMedGoogle Scholar 17 Colhoun H M. et al . Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet. 2004; 364 685-696 CrossrefPubMedGoogle Scholar Roman N. Casciano, MS Analytica International, European Office Untere Herrenstraße 25 79539 Lörrach Email: rcasciano@de.analyticaintl.com
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