Objectives: Presentation of a case report to demonstrate the efficacy and safety of a lifestyle intervention only on glycemic control in a person with newly diagnosed type 2 diabetes and significantly elevated HbA1c level.
Methods: A 48-year-old male patient was diagnosed with type 2 diabetes mellitus (HbA1c 10.3%). The patient participated in the BELIFE study (NCT03827382), a randomized, controlled trial comparing an intensive lifestyle regimen to standard of care in patients with newly diagnosed type 2 diabetes. The intervention group encompasses an intensified lifestyle approach with increased physical activity three to five aerobic training sessions per week (15-40 minutes each), two strength training sessions, and psychological coaching once a week for three months without any antidiabetic medication. Daily activity was monitored using a blinded activity tracker. Blood glucose levels and body composition are checked at randomization and after three months using bioelectrical impedance analysis (BIA).
Results: HbA1c level decreased from 10.3% to 6.0% within three months with lifestyle modification only. Body weight remained stable at 98.4 kg (BMI 31.8 kg/m2). Simultaneously, a decline in fat mass of 3.2 kg (from 31.6 kg to 28.4 kg) and a gain in skeletal muscle mass of 1.5 kg (from 32.7 kg to 34." /> Introduction: The standard therapeutic approach for patients manifesting with newly diagnosed type 2 diabetes and HbA1c levels above 10% involves prompt pharmacotherapy, frequently incorporating insulin underestimating the potential impact of lifestyle changes. The BELIFE study investigates the effect of a lifestyle intervention in patients with uncontrolled newly diagnosed type 2 diabetes (HbA1c > 7.5%) on glucose control. We report an illustrating patient vignette of this trial.
Objectives: Presentation of a case report to demonstrate the efficacy and safety of a lifestyle intervention only on glycemic control in a person with newly diagnosed type 2 diabetes and significantly elevated HbA1c level.
Methods: A 48-year-old male patient was diagnosed with type 2 diabetes mellitus (HbA1c 10.3%). The patient participated in the BELIFE study (NCT03827382), a randomized, controlled trial comparing an intensive lifestyle regimen to standard of care in patients with newly diagnosed type 2 diabetes. The intervention group encompasses an intensified lifestyle approach with increased physical activity three to five aerobic training sessions per week (15-40 minutes each), two strength training sessions, and psychological coaching once a week for three months without any antidiabetic medication. Daily activity was monitored using a blinded activity tracker. Blood glucose levels and body composition are checked at randomization and after three months using bioelectrical impedance analysis (BIA).
Results: HbA1c level decreased from 10.3% to 6.0% within three months with lifestyle modification only. Body weight remained stable at 98.4 kg (BMI 31.8 kg/m2). Simultaneously, a decline in fat mass of 3.2 kg (from 31.6 kg to 28.4 kg) and a gain in skeletal muscle mass of 1.5 kg (from 32.7 kg to 34." />
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