CareLit Fachartikel
Prebiotic inulin and sodium butyrate attenuate barrier dysfunction by induction of antimicrobial peptides in diet-induced obese mice
Beisner, J.; Rosa, L.F.; Kaden-Volynets, V.; Bischoff, S. · Aktuelle Ernährungsmedizin · 2020 · Heft 3 · S. 1 bis 1
Dokument
327924
CareLit-ID
Jahr
2020
Publikation
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Zusammenfassung
Obesity and related metabolic comorbidities represent the most relevant diet-induced diseases. An impaired intestinal barrier function has been associated with obesity and may therefore play a critical role in the development of the disease. In previous work we have shown that the intestinal barrier function is impaired in mice receiving a high-fat and high-sugar diet, so called Western-style diet (WSD). High sugar and high fat consumption causes an increase in intestinal permeability, bacterial endotoxin translocation and subsequent liver steatosis. Besides this, WSD-fed mice are characterized by decreased α-de…
Schlagworte
Gesundheit
Pflege
Diet
Butyrate
Obesity
Work
Aktuelle Ernährungsmedizin
