CareLit Fachartikel
Lipidperoxidation In Parenteral Nutrition: Sensitivity of a Novel Potential Routine Lab Method And Its Compliance To Efsa Requirements
Castelletti, G.; Neyer, P.; Saxer, C.; Mühlebach, S. · Aktuelle Ernährungsmedizin · 2025 · Heft 2 · S. 1 bis 1
Dokument
349614
CareLit-ID
Jahr
2025
Publikation
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Metadaten
DOI
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Zusammenfassung
Introduction: The extent of lipid peroxidation (LPO) is critical for the safe use of in all-in-one (AiO) parenteral nutrition (PN) admixtures. Admixed nutrients, such as trace elements or drugs, can further induce LPO. However, no well-defined and rapid lab assay exists for routine quantification of the most relevant toxic end products. Polyunsaturated fatty acids (PUFA), essential lipid components in PN and regular food, are highly susceptible to (per-)oxidation, forming toxic byproducts like malondialdehyde (MDA), 4-hydroxy-2-hexenal (HHE), and 4-hydroxy-2-nonenal (HNE). These compounds compromising PN quality…
Schlagworte
Lipidperoxidation
Parenterale Ernährung
Labormethode
EFSA-Anforderungen
Nährstoffstabilität
Oxidativer Stress
Lipid Peroxidation
Parenteral Nutrition
Nutritional Support
Oxidative Stress
Food Safety
Laboratory Techniques
Aktuelle Ernährungsmedizin
