Wissenschaftliche Stellungnahme: Norethisteronacetat (NETA) - eine Risikosubstanz?

Summary For many years, breast cancer has been a main issue in the discussions concerning the effects of natural and synthetic steroids. Numerous theories and hypotheses on the etiology of breast cancer have been advanced and rejected. During the last years the discussion has gained intensity. Based on in vitro-investigations with breast cancer cell lines which revealed an inhibitory effect of progestogens on proliferation when continuously present, it was assumed that continuous combined hormone replacement therapy (HRT) protects against breast cancer [, ]. The available epidemiological data, however, failed to…