CareLit Fachartikel

Phase I Trial with an Isoflavonoid Rich Soy/Milk/Honey Supportive Nutrition for Including Into Therapy-Optimizing-Protocols in Oncology

Kurt S. Zänker, G. Gottschalk, H. Adlercreutz · Deutsche Zeitschrift für Onkologie · 2001 · Heft 04 · S. 136-139

Dokument
1006866
CareLit-ID
Jahr
2001
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Deutsche Zeitschrift für Onkologie
Autor:innen
Kurt S. Zänker, G. Gottschalk, H. Adlercreutz
Ausgabe
Heft 04 / 2001
Jahrgang 33
Seiten
136-139
Erschienen: 2001-01-01 00:00:00
ISSN
1617-5891
DOI
10.1055/s-2001-19434

Zusammenfassung

Summary A Phase I study was carried out with an isoflavonoid rich soy/milk/honey product (Somisan®) with the purpose to evaluate the efficacy of such a product for further inclusion into therapy-optimising- studies (TOS). According to a modified Fibonacci-scheme, no adverse side effects, allergy or atopy occurred in 20 subjects enrolled. The optimal dosage was determined with 50 g to 75 g of Somisan®. This dose range caused individual serum levels of diphenolic phyto-oestrogens, like genistein and daidzein, close to that, which are common in Asian people consuming regularly soybean products (Tofu, Miso paste). F…

Schlagworte

Soybean products therapy-optimising-studies (TOS) isoflavonoids Tumor Breast Diet Deutsche Zeitschrift für Onkologie