Long-term efficacy of laparascopic Nissen fundoplication

Background: Laparascopic Nissen fundoplication was introduced to treat therapy-resistant gastro-esophageal reflux disease (GERD), but the long-term efficacy of the procedure is not exactly known. The aim of this study was to investigate the results of total fundic wrap five years after the operation. Methods: Upper GI endoscopy, esophageal manometry (Synetics-Medtronic, Sweden), 24 hr pH-metry, gastrointestinal quality of life index questionnaire (GIQLI) was performed by all patients preoperatively and five years after fundoplication. Results: 7/10 patients had erosive reflux disease (ERD), 3/10 patients had non…