Combined EEG and MEG Source Analysis of Interictal Epileptiform Activity in Childhood Epilepsy

Purpose: MEG is used as a non-invasive tool in an increasing number of epilepsy patients in the context of a presurgical evaluation. However, few studies applied simultaneous surface EEG in the determination of potential epileptogenic zones. A combination of both methods offers a clear benefit, since MEG only detects activities from neurons with tangential orientation and the EEG signal is dominated by radial sources. Patients: We report on 21 children and adolescents with different forms of cortical lesions (FCD 9, PMG 7, other 5) and partial epilepsy. 6 patients presented with CSWS. Methods: 122-channel whole-…