Presurgical Multimodal Imaging in Patients with Cerebral Tumors
RJ Seitz, J Nickel, M Sabel, R Kleiser, S Joergens, L Tellmann, H Neeb, T Stoecker, JN Shah, D Pauleit, G Stoffels, KJ Langen, P Indefrey, W Stummer, H Herzog · Klinische Neurophysiologie · 2004 · Heft 08
Bibliografische Angaben
Zusammenfassung
We introduce a concept for presurgical localization of speech and motor function, which we apply to patients with brain tumors located near eloquent cortex regions. By using standard hard- and software which enables the coregistration of brain structure, amino acid uptake and brain function into one stereotactic dataset, a refined planning of tumor surgery is feasible. The cortical localization for finger-tapping and syntactic speech processing with fMRI (block design, TR time 4000 ms, FOV 200mm, 30 slices à 4mm each frame, gap 0.4mm) is based on two recently validated paradigms. PET imaging is done using the am…