Influence of Selective Norepinephrine Reuptake Inhibition on Motor Function Recovery after Focal Cortical Brain Infarction

Earlier studies suggested that the neurotransmitter norepinephrine (NE) plays a major role in motor function recovery. Stimulation of central norepinephrine was postulated to enhance cortical excitability. This, in turn, is thought to influence functional recovery after focal cortical infarction. Reboxetine is a selective norepinephrine (NE) reuptake inhibitor and a clinically efficacious antidepressant drug. Thus, Reboxetine might facilitate functional recovery and cortical reorganization after ischemic stroke, and it might potentiate the benefit of other neurorehabilitation strategies. The objective of this st…