Capsaicin receptor (CR), substance P (SP) and calcitonin gene releated peptide (CGRP) in patients with different gastrointestinal disorders
A Dömötör, Zs Peidl, A Pár, G Pár, B Gasztonyi, Á Király, L Kereskay, Gy Szekeres, J Szolcsányi, Gy Mózsik · Zeitschrift für Gastroenterologie · 2005 · Heft 05
Bibliografische Angaben
Zusammenfassung
Aims: By stimulating the capsaicin-sensitive nerves with capsaicin, SP and CGRP are released from these nerve endings. We were proved that these fibers and mechanism take place in the development of gastrointestinal mucosal damage/prevention (Mózsik, Abdel-Salam, Szolcsányi: Capsaicin-Sensitive Afferent Nerves in Gastric Mucosal Damage and Protection. Akadémiai Kiadó, Bp. 1997). The aims of our study were to detect the immundistribution of CR1, SP and CGRP in different human gastric and large bowel disorders. Materials and methods: 127 samples were taken from 106 subjects (57 males, 49 females, age: 21–84) suffe…
