Automated CSF cytology – is conventional cytology still necessary?

Objective: To evaluate precision and clinical applicability of the Bayer „Advia 120“ cytometer for CSF cell count and differentiation. Methods: 106 analyses of CSF from 98 patients by the ADVIA 120 were compared with routine cell count and microscopic differentiation and correlation coefficients calculated. Results: In general, the total cell counts of both methods correlated well. The best correlations were seen at higher cell counts over 100 cells/ µL with less than 100 erythrocytes/ µL. The best correlations of cell differentiation were seen for lymphocytes and neutrophils, while the results for monocytes and…