DWI identifies tissue change due to prolonged ictal activity in stroke-related epilepsy
K Szabo, J Hirsch, B Pohlmann-Eden, O Sedlaczek, M Griebe, R Kern, M Hennerici, A Gass · Aktuelle Neurologie · 2005 · Heft 10
Bibliografische Angaben
Zusammenfassung
Background: DWI has been shown to detect acute ischemic lesions and also to detect early tissue changes related to ictal activity. Focally reduced water diffusion and lactate accumulation result from metabolic compromise due to prolonged ictal overactivation. Several studies have demonstrated reduced ADCs in patients with complex partial status epilepticus (CPSE). Methods: We report 10 patients with acute unexplained prolonged clinical deficits (mean 5.3h) – (e.g. hemiparesis, somnolence, confusion) and a differential diagnosis of focal cerebral ischemia and/or CPSE. Patients had a history of chronic territorial…