Different stress-induced membrane molecule profile of circulating lymphocytes in patients with psoriasis and healthy controls

Purpose of study: Psychological stress is assumed to be an important factor for the deterioration of psoriasis (Pso). The goal of the study was to focus on the effects of an established psychological laboratory stress model into immunologic parameters i.e. membrane molecules relevant to the pathophysiology of Pso. Subject sample and statement of methods: Patients with Pso (n=15) and healthy controls (HC, n=15) were exposed to a standardized short laboratory psychological stress, as previously described. In vitro analyses were conducted 1 hour before, immediately after, and 1 hour after stress exposure. Lymphocyt…