Assessment of microvascular characteristics of meningeomas with T1-weighted dynamic contrast-enhanced MRI
J Harrer, GJM Parker, T Krings, HA Haroon, DL Buckley, C Roberts, J Noth, A Thron, A Jackson · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
Purpose: Pharmacokinetic parameters allow the assessment of angiogenic activity in tumours and inflammatory processes. We aimed to characterize different types of meningeoma by estimating vascular permeability and perfusion using T1-weighted dynamic-contrast-enhanced MRI (DCE-MRI). Two established kinetic models were to be applied for analysis and compared intraindividually. Fig. 1 Fig. 2 Materials and methods: DCE-MRI was carried out in eight meningeoma patients. After baseline T1 mapping, contrast-enhanced T1-weighted-3D-FFE sequences were acquired over 40 time points using a 0.1mmol/kg bolus of Gd-DTPA. Two k…
