Alloimmune neonatal neutropenia: Presentation of three cases and review of the literature

We report on three cases of isolated prolonged neutropenia that occurred in preterm neonates and were all due to maternal alloimmunization. Case 1: Male, gestational age 35+3 weeks, birth weight 1650g. The first postnatal white blood cell count (WBCC) showed leukocytopenia of 6860/µl and neutropenia of 686/µl. Subsequently, the leucocyte and neutrophil numbers further decreased to minimum levels of 3190/µl and 120/µl, respectively. From day 14 to 17, both the total WBCC and the neutrophil count showed a progressive increase towards their normal ranges. Case 2: Male, gestational age 35+3 weeks, birth weight 2410g…