5 Years Experience in 33 Preterms and Newborns at High Risk of Perinatal HIV-1 Transmission: HIV-1 Negative after a Triple Antiretroviral Prophylaxis

Background: The low rate of vertical HIV-1 transmission of 1–2% in HIV-1 positive pregnant women has been achieved in Germany since 1995 by the combination of antiretroviral therapy for pregnant woman, caesarean section before onset of labor, refraining from breastfeeding and antiretroviral prophylaxis of the newborn. According to German-Austrian Guidelines in case of high risk of HIV-1 transmission for the newborn a triple antiretroviral prophylaxis is recommended. These guidelines are regularly updated by interdisciplinary consensus meetings, latest in 2005. Methods: In current update an Increase of HIV-1 Vira…