Cortical excitability during movement preparation and rest in patients with Gilles de la Tourette syndrome
K.F Heise, B Steven, G Thomalla, J Hoppe, M Jonas, T Bäumer, K Müller-Vahl, A Münchau, C Gerloff, F Hummel · Aktuelle Neurologie · 2008 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: Patients suffering from Gilles de la Tourette syndrome (GTS) show differences in cortical excitability compared to controls during rest determined by TMS (1). It is unknown how cortical excitability is modulated during movement preparation. In healthy controls, preparation of a voluntary movement of the hand is associated with changes in motor cortical excitability including release of inhibition in the contralateral M1 (2). Aim of the present study was to determine cortical excitability during movement preparation and rest in GTS patients and compare it with healthy controls. Methods: Paired-pulse T…
