CareLit Fachartikel

Dysregulation of the circulating and local Renin-Angiotensin System in preeclampsia

F Herse, N Harsem, S Verlohren, G Wallukat, J Janke, AC Staff, R Dechend · Geburtshilfe und Frauenheilkunde · 2006 · Heft 09

Dokument
1011449
CareLit-ID
Jahr
2006
Publikation
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Bibliografische Angaben

Zeitschrift
Geburtshilfe und Frauenheilkunde
Autor:innen
F Herse, N Harsem, S Verlohren, G Wallukat, J Janke, AC Staff, R Dechend
Ausgabe
Heft 09 / 2006
Seiten
–
Erschienen: 2006-09-19 00:00:00
ISSN
0016-5751
DOI
10.1055/s-2006-952294

Zusammenfassung

The renin-angiotensin system (RAS) has been implicated in the pathogenesis of preeclampsia. Circulating and local RAS was investigated in preeclamptic (n=11) and uneventful pregnancies (n=10) at cesarean delivery. Maternal serum, subcutaneous adipose tissue, placental biopsies and decidual vacuum suction material was collected. Renin Activity and the presence of autoantibody against the AT1 Receptor (AT1R-AA) were measured. We also measured mRNA expression of Renin, Renin Receptor (ReRe), Angiotensinogen (Aogen), Angiotensin-Converting enzyme (ACE), AT1 Receptor and AT2 Receptor in decidua, placenta and adipose…

Schlagworte

Geburtshilfe und Frauenheilkunde