Treatment of ovulatory dysfunctional uterine bleeding with oral misoprostol: a comparative study

Objectives: Evaluation of the effects of oral misoprostol in the control of excessive menstrual blood loss in cases of ovulatory dysfunctional uterine bleeding in comparison to antifibrinolytic and antiprostaglandin therapy. Methods: Eighty-six patients with objective menorrhagia secondary to ovulatory dysfunctional uterine bleeding completed this prospective randomized comparative clinical trial of treatment with tranexamic acid(31 patients-group I), misoprostol(29 patients-group II), and mefenamic acid(26 patients-group III). Treatment was given during menstruation for three cycles. Treatment started on day on…