Preserved eye-hand coordination in spinocerebellar ataxia type 17
P. Trillenberg, A. Sprenger, A. Hiller, C. Klein, G. Weinberger, S. Krug, A. Rolfs, C. Helmchen · Aktuelle Neurologie · 2006 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background/Aim: SCA17 is caused by a trinucleotide expansion in the gene encoding the TATA binding protein (TBP). We intended to characterize combined eye-hand movements in this ataxic disorder by using hand pointing tasks. Methods: Subjects were included after molecular genetic diagnosis of SCA17. Hand pointing movements were recorded in 12 patients and 12 controls matched for age with an ultrasound based system (ZEBRIS). Eye movements were recorded with the video-based EYELINK II system. Subjects were asked to point towards targets at 8° and 12° to the left and to the right, respectively. In different conditio…
