Transcriptome analysis of peripheral blood mononuclear cells from stroke survivors
C. Grond-Ginsbach, S. Horstmann, T. Wiest, C. Honold, U. Mansmann, K. Pfleger, M. Hergenhahn, A. Weninger, S. Wagner, A. Grau · Aktuelle Neurologie · 2006 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background and purpose: The simultaneous analysis of thousends of different RNA species by GeneChip analysis (expression profiling) enables the study of functionally coordinated genetic pathways rather than the analysis of single genes. In this study we aimed to identify differences in gene expression in circulating white blood cells from stroke survivors and healthy control subjects. Methods: RNA from peripheral blood mononuclear cells (PBMCs) of 15 stroke survivors and 15 healthy referent subjects was analyzed with GeneChips. Gene expression was studied either immediately after blood sampling or after 2 hours…
