Prognostic Value of Transient Elastography for the Outcome of Acute Liver Failure

Transient elastography (FS) has been validated for the evaluation of liver stiffness in chronic hepatopathy. However, anecdotal evidence also indicated characteristic alterations in liver stiffness in acute liver failure (ALF). By correlation with well-established markers of hepatic fibrosis, the present prospective study thus focused on clarifying the potential prognostic value of FS values in ALF patients. Methodology: 17 patients (age=43 yrs. / 8 f and 9 m) with clinical signs of ALF due to HBV infection (n7), drug toxicity (n6), mycotoxicosis (n4), heart failure (n2), or of indeterminate etiology (n4) were i…