Quantitative lung morphology in a regenerative lung model

Einleitung: Several lung diseases are caused by the loss of alveolar septae or alveolar remodelling. But the ability of some mammals to regenerate the lungs provides an opportunity to study regenerative mechanisms. Understanding these mechanisms will provide us with a rationale for the therapeutic purpose. The aim of our study is to decipher lung regeneration at cellular and structural levels using a stereological approach in a murine calorie restriction model. Methoden: Calorie restriction murine model, stereological methods to study structural parameters such as alveolar number, alveolar volume, alveolar wall…