CareLit Fachartikel
Claudin expression in different pancreatic cancers and its significance in differential diagnostics
K Borka, A Korompay, E Szabó, P Kaliszky, P Kupcsulik, Z Schaff, A Kiss · Zeitschrift für Gastroenterologie · 2009 · Heft 05
Dokument
1012272
CareLit-ID
Jahr
2009
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Zusammenfassung
Introduction: Claudins (CLDNs) are essential proteins of tight junctions. Changes in their expression pattern have been demonstrated in a number of tumors. CLDNs-3 and -4 are receptors of the Clostridium perfringens enterotoxin, cytolytic effects of the toxin are well known. The aim of our studies was to compare the different CLDN expression patterns in normal pancreas cells, pancreatic endocrine tumors, adenocarcinomas, mucinous cystic tumors and acinar cell carcinomas. Material and methods: Retrospective series of 74 formalin fixed, paraffin embedded tissues were obtained from the archives of the 2nd Departmen…
Schlagworte
Clostridium perfringens
Cushing Syndrome
Acinar Cells
Clostridium
Diagnosis
Archives
Claudins
Zeitschrift für Gastroenterologie
