Phylogenetic analysis of a hepatitis C virus outbreak in a haemodialysis unit

Introduction: Since the screening of blood donors has been introduced, transfusion-associated hepatitis C infections have become rare events. However, a part of newly acquired HCV infections are still health-care related. By the phylogenetic analysis of viral sequences the relatedness of new infections can be demonstrated. In this study we aimed to find molecular evidence for a nosocomial transmission and to ascertain the source of infections at a haemodialysis center in Hungary. 25 seropositive patients were included in the analysis, 4 of them had been known hepatitis C virus carriers previous to haemodialysis…