Gut permeability in patients with irritable bowel syndrome and inactive ulcerative colitis

Introduction: Elevated colonic permeability has previously been reported in our preliminary study in the diarrhea-predominant subgroup of patients with irritable bowel syndrome (IBS-D). There is growing evidence for low grade mucosal inflammation in IBS, therefore comparing permeability data on inflammatory bowel disease and IBS may be an interesting issue of future investigations concerning the pathomechanism of IBS. Aims: The aim of this study was to evaluate gut permeability in patients with inactive ulcerative colitis in comparison with subgroups of IBS patients and control subjects. Methods: IBS patients of…