No evidence of hippocampal sclerosis in healthy subjects on magnetic resonance imaging
A Plate, K Hattemer, J Iwinska-Zelder, K Shiratori, RK Jäger, WH Oertel, HM Hamer, F Rosenow, S Knake · Aktuelle Neurologie · 2009 · Heft 10
Bibliografische Angaben
Zusammenfassung
Purpose: The presence of hippocampal sclerosis on MRI has a great impact for the treatment of patients with temporal lobe epilepsy. It influences the clinical evaluation and counselling and is considered as a key criterion for the decision to recommend epilepsy surgery in patients with temporal lobe epilepsy (TLE). However, neuropathological studies describe evidence of hippocampal sclerosis (HS) in up to 10% of non-epileptic patients, challenging the impact of MRI findings in patients with TLE. Therefore, we evaluated the prevalence of hippocampal sclerosis on MRI in the general population, using a specific pro…