Progressive sclerosing cholangitis after shock: a long-term follow-up study

Introduction: In 2003 we have described a new form of sclerosing cholangitis (Gut 52, 2003: 688–93). We now present a long-term follow-up study of 25 patients with progressive sclerosing cholangitis treated between 1994 and 2006. Patients and Methods: All patients, who had no evidence of pre-existing hepatobiliary disease, had previously required long-term treatment in an intensive care unit for septic shock. Results: All patients had cholestasis of unknown origin. Therefore, ERCP was performed showing severe intrahepatic stenosis with rarefaction of the small bile ducts in all patients. The bile ducts were part…