Prognostic Factors for Carcinoma of Unknown Primary Localized to the Neck only (CUP Syndrome) and the Role of F-18-FDG PET for Diagnosis and Therapeutic Management

Ziele: Treatment of patients with carcinoma of unknown primary localized to the neck only is still controversial. To determine both patient related prognostic factors and the influence of treatment parameters in addition to the role of F-18-FDG PET for diagnostics and therapy management 132 patients with carcinoma of unknown primary localized to the neck only were analyzed. Methode: Surgery as a sole treatment (n=51). Combination of surgery and radiation therapy (n=48). Statistical analyses: Kaplan-Meier, log-rank-test, chi-square-test. All PET studies (n=41) were carried out after conventional diagnostic proced…