Insulin resistance and biochemical response rates in treated chronic hepatitis C patients

Aims: the response rate in chronic hepatitis C (CHC) patients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV) is multifactorial, and associated with bad prognosis in cases of insulin resistance (IR) and/or hepatic steatosis. Aim: to clarify the association between the main factors of IR and the biochemical response in patients treated with PEG-IFN+ RBV were studied. Patients and methods: 62, PEG-IFN and RBV treated patient's data were studied. We measured the body weight, BMI (body mass index), waist circumference, HOMA (homeostasis assesment modell) index, serum glucose, cholesterol and insulin…